Itazigrel
Names
[ CAS No. ]:
70529-35-0
[ Name ]:
Itazigrel
[Synonym ]:
4,5-bis(p-Methoxyphenyl)-2-(trifluoromethyl)thiazole
2-Trifluormethyl-4,5-bis(p-methoxyphenyl)thiazole
Itazigrelum [Latin]
Itazogrel
ITAZIGREL
4,5-bis-(4-methoxy-phenyl)-2-trifluoromethyl-thiazole
2-Trifluormethyl-4,5-di-p-anisylthiazol
Chemical & Physical Properties
[ Density]:
1.285g/cm3
[ Boiling Point ]:
400.3ºC at 760 mmHg
[ Molecular Formula ]:
C18H14F3NO2S
[ Molecular Weight ]:
365.36900
[ Flash Point ]:
195.9ºC
[ Exact Mass ]:
365.07000
[ PSA ]:
59.59000
[ LogP ]:
5.51310
[ Index of Refraction ]:
1.547
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XJ2983000
- CHEMICAL NAME :
- Thiazole, 4,5-bis(4-methoxyphenyl)-2-trifluoromethyl-
- CAS REGISTRY NUMBER :
- 70529-35-0
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C18-H14-F3-N-O2-S
- MOLECULAR WEIGHT :
- 365.39
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4659726
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THHADQ Thrombosis and Haemostasis. (F.K. Schattauer Verlag, Postfach 104545, D-70040 Stuttgart, Germany) V.35- 1976- Volume(issue)/page/year: 46,26,1981