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Chlorothiazide Sodium

Names

[ CAS No. ]:
7085-44-1

[ Name ]:
Chlorothiazide Sodium

[Synonym ]:
Sodium diuril
C7H5ClN3O4S2.Na
6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide,1,1-dioxide,monosodium salt
EINECS 230-387-3
2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-,1,1-dioxide,monosodium salt
Diuril sodium
SN86FG7N2K
CHLOROTHIAZIDE SODIUM
UNII-SN86FG7N2K

Biological Activity

[Description]:

Chlorothiazide sodium is an orally active diuretic and anti-hypertensive agent[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[In Vitro]

Chlorothiazide sodium has a plasma half-life of 45–120 min and a biological half-life of nearly 10 h[1].

[References]

[1]. Babu V R, et al. Preparation and in-vitro release of chlorothiazide novel pH-sensitive chitosan-N, N′-dimethylacrylamide semi-interpenetrating network microspheres. Carbohydrate Polymers, 2008, 71(2): 208-217.

Chemical & Physical Properties

[ Molecular Formula ]:
C7H6ClN3NaO4S2

[ Molecular Weight ]:
318.71300

[ Exact Mass ]:
317.93900

[ PSA ]:
135.45000

[ LogP ]:
2.56540

Related Compounds