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3,4-Methylenedioxytoluene

Names

[ CAS No. ]:
7145-99-5

[ Name ]:
3,4-Methylenedioxytoluene

[Synonym ]:
Toluene,3,4-methylenedioxy
1,3-Benzodioxole, 5-methyl-
3,4-Methylenedioxytoluene
4-methyl-methylenedioxybenzene
1,3-Benzodioxole,5-methyl
MFCD00005833
1-methyl-3,4-methylenedioxybenzene
EINECS 230-453-1
5-METHYL-1,3-BENZODIOXOLE

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
200.4±30.0 °C at 760 mmHg

[ Molecular Formula ]:
C8H8O2

[ Molecular Weight ]:
136.148

[ Flash Point ]:
76.1±0.0 °C

[ Exact Mass ]:
136.052429

[ PSA ]:
18.46000

[ LogP ]:
2.54

[ Vapour Pressure ]:
0.5±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.550

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DF4921090
CHEMICAL NAME :
1,3-Benzodioxole, 5-methyl-
CAS REGISTRY NUMBER :
7145-99-5
LAST UPDATED :
199706
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H8-O2
MOLECULAR WEIGHT :
136.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,230,1954

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DF4921090

Synthetic Route

Precursor & DownStream

Articles

The dimethoxyphenylbenzyl protecting group: an alternative to the p-methoxybenzyl group for protection of carbohydrates.

J. Org. Chem. 78(11) , 5264-72, (2013)

A reliable reagent system for the cleavage of 4-(3,4-dimethoxyphenyl)benzyl (DMPBn) ethers under acidic conditions has been established. Treatment of DMPBn-protected mono- and pseudodisaccharides with...


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