2-(Difluoromethoxy)benzaldehyde
Names
[ CAS No. ]:
71653-64-0
[ Name ]:
2-(Difluoromethoxy)benzaldehyde
[Synonym ]:
Benzaldehyde, 2-(difluoromethoxy)-
MFCD00042251
2-(Difluoromethoxy)benzaldehyde
α,α-Difluoro-o-anisaldehyde
VHR BOYFF
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
226.6±30.0 °C at 760 mmHg
[ Molecular Formula ]:
C8H6F2O2
[ Molecular Weight ]:
172.129
[ Flash Point ]:
88.4±19.4 °C
[ Exact Mass ]:
172.033585
[ PSA ]:
26.30000
[ LogP ]:
1.89
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.498
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2913000090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2913000090
[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%
Articles
J. Org. Chem. 67(2) , 401-10, (2002)
Since 2,6-dimethyl-4-aryl-1,4-dihydropyridine 3,5-diesters themselves are not hydrolyzed by commercially available hydrolases, derivatives with spacers containing a hydrolyzable group were prepared. S...
Synthesis of 3-alkoxycarbonyl-6-alkylsulfanyl-4-[2-(difluoromethoxy) phenyl]-1, 4-dihydropyridines and related derivatives as analogs of cognition enhancer cerebrocrast. Krauze A, et al.Chem. Heterocycl. Comp. 49(4) , 566-73, (2013)
Synthesis and enantioselective lipase-catalyzed kinetic resolution of methyl 6-(methoxycarbonyl-methyl) sulfanyl-1, 4-dihydropyridine-3-carboxylates. Andzans Z, et al.
Chem. Heterocycl. Comp. 49(13) , 421-27, (2013)