1,4-Bis(3-aminopropyl)piperazine

Names

[ Name ]:
1,4-Bis(3-aminopropyl)piperazine

[Synonym ]:
MFCD00006161
1,4-Piperazinedipropanamine
3,3'-(1,4-Piperazinediyl)di(1-propanamine)
EINECS 230-589-1
1,4-Bis(3-aminopropyl)piperazine
3,3'-PIPERAZINE-1,4-DIYLDIPROPAN-1-AMINE
BAPPRZ
BIS AMINOPROPYL PIPIRAZINE

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
334.5±0.0 °C at 760 mmHg

[ Melting Point ]:
15 °C(lit.)

[ Molecular Formula ]:
C₁₀H₂₄N₄

[ Molecular Weight ]:
200.324

[ Flash Point ]:
162.8±0.0 °C

[ Exact Mass ]:
200.200104

[ PSA ]:
58.52000

[ LogP ]:
-1.43

[ Vapour density ]:
6.9 (vs air)

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.505

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S27-S28-S36/37/39-S45

[ RIDADR ]:
UN 2735 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
TK8700000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Multifunctional disulfide-based cationic dextran conjugates for intravenous gene delivery targeting ovarian cancer cells.

Mol. Pharm. 11(7) , 2250-61, (2014)

A folate-decorated, disulfide-based cationic dextran conjugate having dextran as the main chain and disulfide-linked 1,4-bis(3-aminopropyl)piperazine (BAP) residues as the grafts was designed and succ...

Thermodynamic Investigation and Mixed Ligand Complex Formation of 1,4-Bis-(3-aminopropyl)-piperazine and Biorelevant Ligands.

Bioinorg. Chem. Appl. 2012 , 984291, (2012)

Thermodynamic parameters for protonation of 1,4-bis(3-aminopropyl)-piperazine (BAPP) and its metal complexation with some divalent metal ions were determined in aqueous solution at constant ionic stre...

Multifunctional cationic polyurethanes designed for non-viral cancer gene therapy.

Acta Biomater. 30 , 155-67, (2015)

Nano-polyplexes from bioreducible cationic polymers have a massive promise for cancer gene therapy. However, the feasibility of cationic polyurethanes for non-viral gene therapy is so far not well stu...