1-(2-Pyridinyl)-4-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl) piperazine
Names
[ CAS No. ]:
72141-45-8
[ Name ]:
1-(2-Pyridinyl)-4-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl) piperazine
Chemical & Physical Properties
[ Density]:
1.364g/cm3
[ Boiling Point ]:
652.7ºC at 760 mmHg
[ Molecular Formula ]:
C26H22F3N5O
[ Molecular Weight ]:
477.48100
[ Flash Point ]:
348.5ºC
[ Exact Mass ]:
477.17800
[ PSA ]:
61.36000
[ LogP ]:
5.43050
[ Index of Refraction ]:
1.652
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TM2765200
- CHEMICAL NAME :
- Piperazine, 1-(2-pyridinyl)-4-(4-((7-(trifluoromethyl)-4-quinolin yl)amino)benzoyl)-
- CAS REGISTRY NUMBER :
- 72141-45-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C26-H22-F3-N5-O
- MOLECULAR WEIGHT :
- 477.53
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1395 mg/kg
- TOXIC EFFECTS :
- Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 29,133,1986