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3-Amino-1-methyl-5H-pyrido(4,3-b)indole

Names

[ CAS No. ]:
72254-58-1

[ Name ]:
3-Amino-1-methyl-5H-pyrido(4,3-b)indole

[Synonym ]:
3-amino-1-methyl-5H-pyrido<4,3-b>indole-acetate salt
1,4-Dimethyl-5H-pyrido[4,3-b]indol-3-amine Monoacetate
acetic acid salt of 3-amino-1,4-dimethyl-5H-pyrido<4,3-b>indole
Trp-P-2 acetate
Tryptophan p 1 acetate
3-b)indole,3-amino-1,4-dimethyl-5h-pyrido(acetate
Tryptophan p 2 acetate
3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole acetate salt
3-b)indol-3-amine,1,4-dimethyl-5h-pyrido(monoacetate
3-Amino-1-methyl-5H-pyrido[4,3-b]indole acetate
3-b)indol-3-amine,1,4-dimethyl-5h-pyrido(acetate
Trp-P-1 acetate
acetic acid salt of 3-amino-1-methyl-5H-pyrido<4,3-b>indole
1-methyl-5H-pyrido[4,3-b]indol-3-ylammonium acetate
3-Amino-1-methyl-5H-pyrido<4,3-b>indol-Acetat

Chemical & Physical Properties

[ Density]:
1.334g/cm3

[ Boiling Point ]:
455.7ºC at 760 mmHg

[ Melting Point ]:
>300ºC

[ Molecular Formula ]:
C12H11N3

[ Molecular Weight ]:
197.23600

[ Flash Point ]:
260.1ºC

[ Exact Mass ]:
197.09500

[ PSA ]:
54.70000

[ LogP ]:
3.18790

[ Index of Refraction ]:
1.806

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU9355000
CHEMICAL NAME :
5H-Pyrido(4,3-b)indole, 3-amino-1-methyl-, acetate
CAS REGISTRY NUMBER :
72254-58-1
LAST UPDATED :
199806
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C12-H11-N3.C2-H4-O2
MOLECULAR WEIGHT :
257.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3011 mg/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
14 gm/kg/89W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors
TYPE OF TEST :
Specific locus test
TYPE OF TEST :
Sister chromatid exchange
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
13 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 395,57,1997

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

Synthetic Route

Precursor & DownStream


Related Compounds