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Tetrahydro-2-phenyl-4H-1,3-thiazin-4-one

Names

[ CAS No. ]:
72286-34-1

[ Name ]:
Tetrahydro-2-phenyl-4H-1,3-thiazin-4-one

[Synonym ]:
2-Phenyl-tetrahydro-[1,3]thiazin-4-on
2-phenyl-tetrahydro-[1,3]thiazin-4-one
(2H)1,3-Oxazine,tetrahydro-2-phenyl
1,3-Oxazine,tetrahydro-2-phenyl
2-phenylperhydro-1,3-oxazine
2-Phenyl-tetrahydro-[1,3]oxazin
2-phenyl-[1,3]thiazinan-4-one
2-phenyl-tetrahydro-(2H)-1,3-oxazine
2-phenyl-tetrahydro-[1,3]oxazine
tetrahydro-2-phenyl-4H-1,3-thiazin-4-one

Chemical & Physical Properties

[ Molecular Formula ]:
C10H11NOS

[ Molecular Weight ]:
193.26500

[ Exact Mass ]:
193.05600

[ PSA ]:
54.40000

[ LogP ]:
2.26710

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ1261700
CHEMICAL NAME :
4H-1,3-Thiazin-4-one, tetrahydro-2-phenyl-
CAS REGISTRY NUMBER :
72286-34-1
BEILSTEIN REFERENCE NO. :
0149651
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H11-N-O-S
MOLECULAR WEIGHT :
193.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 122,517,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - ataxia Vascular - BP lowering not characterized in autonomic section
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 122,517,1957

Synthetic Route

Precursor & DownStream


Related Compounds