1-Ethoxycarbonyl-beta-carboline

Names

[ Name ]:
1-Ethoxycarbonyl-beta-carboline

[Synonym ]:
1-ethoxycarbonyl-β-carboline
Kumujian A
ethyl 9H-pyrido[3,4-b]indole-1-carboxylate
ethyl β-carboline-1-carboxylate
Ethyl β-carboline-4-carboxylate
1-Ethoxycarbonyl-beta-carboline

Biological Activity

[Description]:

Kumujian A (1-Ethoxycarbonyl-β-carboline), an anti-inflammatory agent, inhibits both superoxide anion generation (IC50 = 4.87 μg/mL) and elastase release (IC50 = 6.29 μg/mL)[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. Fang HW, et al. Total synthesis of cordatanine, structural reassignment of drymaritin, and anti-inflammatory activity of synthetic precursors. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3822-4.

Chemical & Physical Properties

[ Density]:
1.308±0.06 g/cm3 (20 ºC 760 Torr)

[ Melting Point ]:
145-146 ºC

[ Molecular Formula ]:
C₁₄H₁₂N₂O₂

[ Molecular Weight ]:
240.25700

[ Exact Mass ]:
240.09000

[ PSA ]:
54.98000

[ LogP ]:
2.89280

[ Water Solubility ]:
Practically insoluble (0.021 g/L) (25 ºC)

1-Ethoxycarbonyl-beta-carboline

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds