BENZYDAMINE N-OXIDE HYDROGEN MALEATE

Names

[ CAS No. ]:
72962-60-8

[ Name ]:
BENZYDAMINE N-OXIDE HYDROGEN MALEATE

[Synonym ]:
Benzydamine N-oxide hydrogen maleate

Chemical & Physical Properties

[ Melting Point ]:
94-95ºC

[ Molecular Formula ]:
C₂₃H₂₇N₃O₆

[ Molecular Weight ]:
441.47700

[ Exact Mass ]:
441.19000

[ PSA ]:
131.08000

[ LogP ]:
3.16040

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Articles

HPLC determination of benzydamine and its metabolite N-oxide in plasma following oral administration or topical application in man, using fluorimetric detection.

Pharmacol. Res. Commun. 18(4) , 385-403, (1986)

A method for the extraction and quantification of benzydamine and its metabolite N-oxide by liquid chromatography with fluorescence detection in plasma samples is described. This method has adequate s...

Determination of benzydamine and its N-oxide in biological fluids by high-performance liquid chromatography.

J. Chromatogr. A. 529(1) , 113-23, (1990)

A simple, sensitive and selective method for the determination of benzydamine in human plasma and urine, and for benzydamine N-oxide in urine, has been developed using high-performance liquid chromato...

Flavin-containing monooxygenase mediated metabolism of benzydamine in perfused brain and liver.

Biochim. Biophys. Acta 1425(1) , 41-6, (1998)

Benzydamine (BZY) N-oxidation mediated by flavin-containing monooxygenase (FMO) was evaluated in perfused brain and liver. Following 20 min of perfusion with modified Ringer solution, the infusion of ...