c19:1 (cis-10) acid

Names

[ Name ]:
c19:1 (cis-10) acid

[Synonym ]:
10(Z)-nonadecenoic acid
cis-10-Nonadecenoic acid
C19:1n-9
Nonadeca-10(Z)-enoic acid
(Z)-10-nonadecenoic acid

Biological Activity

[Description]:

10Z-Nonadecenoic acid is a kind of long-chain fatty acid with anti-tumor activity.

[Related Catalog]:

Natural Products >> Acids and Aldehydes

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[In Vitro]

10Z-Nonadecenoic acid is a kind of long-chain fatty acid with anti-tumor activity[1]. 10Z-Nonadecenoic acid could also inhibit p53 activity[2].

[References]

[1]. Fukuzawa M1, et al. Possible involvement of long chain fatty acids in the spores of Ganoderma lucidum (Reishi Houshi) to its anti-tumor activity. Biol Pharm Bull. 2008 Oct;31(10):1933-7.

[2]. Iijima H, et al. The inhibitory action of long-chain fatty acids on the DNA binding activity of p53. Lipids. 2006 Jun;41(6):521-7.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
0.897g/cm3

[ Boiling Point ]:
384.4ºC at 760 mmHg

[ Molecular Formula ]:
C₁₉H₃₆O₂

[ Molecular Weight ]:
296.48800

[ Flash Point ]:
281.3ºC

[ Exact Mass ]:
296.27200

[ PSA ]:
37.30000

[ LogP ]:
6.49860

[ Appearance of Characters ]:
liquid

[ Index of Refraction ]:
1.467

[ Storage condition ]:
−20°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916190090

[ Summary ]:
2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

Articles

Exploring metabolic syndrome serum free fatty acid profiles based on GC-SIM-MS combined with random forests and canonical correlation analysis.

Talanta 135 , 108-14, (2015)

Metabolic syndrome (MetS) is a cluster of metabolic abnormalities associated with an increased risk of developing cardiovascular diseases or type II diabetes. Till now, the etiology of MetS is complex...