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Chloranthalactone E

Names

[ CAS No. ]:
73215-92-6

[ Name ]:
Chloranthalactone E

[Synonym ]:
(4aS,5aS,6aR,6bS,7S,7aR)-7,7a-Dihydroxy-3,6b-dimethyl-5-methylene-4a,5,5a,6,6a,6b,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one
Cycloprop[2,3]indeno[5,6-b]furan-2(4H)-one, 4a,5,5a,6,6a,6b,7,7a-octahydro-7,7a-dihydroxy-3,6b-dimethyl-5-methylene-, (4aS,5aS,6aR,6bS,7S,7aR)-

Biological Activity

[Description]:

Chloranthalactone E (compound 6), a labdane diterpene, can be isolated from the aerial parts of Chloranthus serratus. Chloranthalactone E inhibits NO production in LPS-activated RAW 264.7 macrophages[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> NO Synthase
Research Areas >> Inflammation/Immunology

[References]

[1]. Zhao M, et al. A new labdane diterpene from the aerial parts of chloranthus serratus. Rec. Nat. Products, 2020, 14: 382.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
458.8±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C15H18O4

[ Molecular Weight ]:
262.301

[ Flash Point ]:
175.6±22.2 °C

[ Exact Mass ]:
262.120514

[ LogP ]:
1.07

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.623

[ Storage condition ]:
2-8℃

Related Compounds