Fluprostenol methyl ester
Names
[ CAS No. ]:
73275-76-0
[ Name ]:
Fluprostenol methyl ester
[Synonym ]:
Methyl (2Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}cyclopentyl]-2-heptenoate
Methyl (5Z)-7-[(2R)-3,5-dihydroxy-2-{(1E)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}cyclopentyl]-5-heptenoate
2-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, methyl ester, (2Z)-
5-Heptenoic acid, 7-[(2R)-3,5-dihydroxy-2-[(1E)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, methyl ester, (5Z)-
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
568.5±50.0 °C at 760 mmHg
[ Molecular Formula ]:
C24H31F3O6
[ Molecular Weight ]:
472.495
[ Flash Point ]:
297.6±30.1 °C
[ Exact Mass ]:
472.207275
[ PSA ]:
96.22000
[ LogP ]:
3.55
[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C
[ Index of Refraction ]:
1.555
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MJ9669900
- CHEMICAL NAME :
- 5-Heptenoic acid, 7-(3,5-dihydroxy-2-(3-hydroxy-4-(3-(trifluoromethyl)p henoxy)-1-butenyl) cyclopentyl)-, methyl ester, (1R-(1-alpha(Z),2-beta(1E,3R*),3-alpha,5-alpha))-
- CAS REGISTRY NUMBER :
- 73275-76-0
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C24-H31-F3-O6
- MOLECULAR WEIGHT :
- 472.55
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 78 ug/kg
- SEX/DURATION :
- female 3-5 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,525,1980