Acetamide,N-[(1R,2R)-2-(4-acetylphenyl)-2-hydroxy-1-(hydroxymethyl)ethyl]-2,2-dichloro-
Names
[ CAS No. ]:
735-52-4
[ Name ]:
Acetamide,N-[(1R,2R)-2-(4-acetylphenyl)-2-hydroxy-1-(hydroxymethyl)ethyl]-2,2-dichloro-
[Synonym ]:
Cetofenicol
CETOPHENICOL
Acetylchloramphenicol
D-Threoacetomycetin
Acetamide,2-dichloro-,D-threo
W 3746
Chemical & Physical Properties
[ Molecular Formula ]:
C13H15Cl2NO4
[ Molecular Weight ]:
320.16900
[ Exact Mass ]:
319.03800
[ PSA ]:
86.63000
[ LogP ]:
1.59430
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AB4200000
- CHEMICAL NAME :
- Acetamide, N-(p-acetyl-beta-hydroxy-alpha-(hydroxymethyl)pheneth yl)-2,2-dichloro-, D-threo-
- CAS REGISTRY NUMBER :
- 735-52-4
- LAST UPDATED :
- 199106
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C13-H15-Cl2-N-O4
- MOLECULAR WEIGHT :
- 320.19
- WISWESSER LINE NOTATION :
- GYGVMY1QYQR DV1 -D -THREO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1097 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,185,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,888,1967