Benzo[e][2]benzopyrano[4,3-b]indol-5(13H)-one

Names

[ Name ]:
Benzo[e][2]benzopyrano[4,3-b]indol-5(13H)-one

[Synonym ]:
Benzo(e)(2)benzopyrano(4,3-b)indol-5-one,5,13-dihydro
5-Oxo-5,13-dihydrobenzo(e)(2)benzopyrano(4,3-b)indole
Benzo(e)(2)benzopyrano(4,3-b)indol-5(13H)-one
benzo[e]isochromeno[4,3-b]indol-5(13h)-one
5H-Benzo<e>isochromeno<4,3-b>indol-5-on
5-Oxo-5H-benzo(e)isochromeno(4,3-b)indole
5,13-Dihydro-5-oxobenzo(e)(2)benzopyrano(4,3-b)indole

Chemical & Physical Properties

[ Density]:
1.425g/cm3

[ Boiling Point ]:
576.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₉H₁₁NO₂

[ Molecular Weight ]:
285.29600

[ Flash Point ]:
302.4ºC

[ Exact Mass ]:
285.07900

[ PSA ]:
46.00000

[ LogP ]:
4.58070

[ Index of Refraction ]:
1.801

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DE5425000

CHEMICAL NAME :: Benzo(e)(2)benzopyrano(4,3-b)indol-5-one, 5,13-dihydro-

CAS REGISTRY NUMBER :: 7374-66-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C19-H11-N-O2

MOLECULAR WEIGHT :: 285.31

WISWESSER LINE NOTATION :: T F6 C6 B566 EO JO MN DHJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 72 mg/kg/9W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

REFERENCE :: SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 158,387,1967 *** REVIEWS *** TOXICOLOGY REVIEW 22HAAD "Microbial Toxins, 1970-72," Ajil, S.J., et al., eds., New York, Academic Press, Inc., 1970-72 Volume(issue)/page/year: 6,409,1971