<Suppliers Price>

Kamebakaurine

Names

[ CAS No. ]:
73981-34-7

[ Name ]:
Kamebakaurine

[Synonym ]:
1,7,14,20-Tetrahydroxykaur-16-en-15-one (1alpha,7alpha,14R)
Kaur-16-en-15-one,1,7,14,20-tetrahydroxy-,(1alpha,7alpha,14R)

Biological Activity

[Description]:

Kamebakaurin is a natural compound isolated from Isodon japonicus. Kamebakaurin is a potent inhibitor of NF-κB activation by directly targeting DNA-binding activity of p50[1].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Inflammation/Immunology

[References]

[1]. Lee JH, et al. Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes. J Biol Chem. 2002 May 24;277(21):18411-20.

Chemical & Physical Properties

[ Density]:
1.3g/cm3

[ Boiling Point ]:
563.5ºC at 760 mmHg

[ Melting Point ]:
7ºC

[ Molecular Formula ]:
C20H30O5

[ Molecular Weight ]:
350.44900

[ Flash Point ]:
308.6ºC

[ Exact Mass ]:
350.20900

[ PSA ]:
97.99000

[ LogP ]:
1.03920

[ Index of Refraction ]:
1.601

Related Compounds