Benzilic acid, 1.alpha.-H,5.alpha.-H-tropan-3.beta.-yl ester
Names
[ CAS No. ]:
74051-39-1
[ Name ]:
Benzilic acid, 1.alpha.-H,5.alpha.-H-tropan-3.beta.-yl ester
[Synonym ]:
Tropine benzilate
3alpha(1alphaH,5alphaH)-Tropanylbenzilat
endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2,2-diphenylacetate
Tropinbenzilat
Glypin
benzilic acid tropane-3exo-yl ester
Glipin
Benzziloyl tropein
(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(diphenyl)acetate
benzilic acid tropane-3endo-yl ester
Tropanyl benzilate
Benzilsaeure-tropan-3exo-ylester
Benzilsaeure-tropan-3endo-ylester
Chemical & Physical Properties
[ Density]:
1.23g/cm3
[ Boiling Point ]:
444.7ºC at 760mmHg
[ Molecular Formula ]:
C22H25NO3
[ Molecular Weight ]:
351.43900
[ Flash Point ]:
222.7ºC
[ Exact Mass ]:
351.18300
[ PSA ]:
49.77000
[ LogP ]:
3.02880
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YM4150000
- CHEMICAL NAME :
- 1-alpha-H,5-alpha-H-Tropan-3-beta-ol, benzilate (ester)
- CAS REGISTRY NUMBER :
- 74051-39-1
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C22-H25-N-O3
- MOLECULAR WEIGHT :
- 351.48
- WISWESSER LINE NOTATION :
- T56 A ANTJ A1 DOVXQR&R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - hematuria
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 14,559,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 22 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 59,149,1938