1-Naphthylacetonitrile

Names

[ Name ]:
1-Naphthylacetonitrile

[Synonym ]:
Naphthalen-1-ylacetonitril
1-Naphthyl acetonitr
1-Naphthylmethylcyanide
1-Naphthyl Acetonitrile
2-naphthalen-2-ylacetonitrile
naphthylacetonitrile
naphth-1-ylacetonitrile
a-naphthylacetonitrile
1-Naphthylacetonitrile
MFCD00004122
naphthalen-1-ylacetonitrile
EINECS 231-352-5
1-Cyanomethylnaphthalene
1-Naphthaleneacetonitrile
α-(1-naphthyl)acetonitrile
α-Naphthylacetonitrile
1-Naphtylacetonitrile
2-(naphthalen-1-yl)acetonitrile

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
323.9±0.0 °C at 760 mmHg

[ Melting Point ]:
82-84 °C(lit.)

[ Molecular Formula ]:
C₁₂H₉N

[ Molecular Weight ]:
167.207

[ Flash Point ]:
180.3±5.7 °C

[ Exact Mass ]:
167.073502

[ PSA ]:
23.79000

[ LogP ]:
2.68

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.634

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S36-S24/25

[ RIDADR ]:
3276

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2926909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Three-component coupling using arynes and DMF: straightforward access to coumarins via ortho-quinone methides.

Chem. Commun. (Camb.) 47(30) , 8512-4, (2011)

ortho-Quinone methides, arising from a formal [2+2] cycloaddition between arynes and DMF, were found to facilely undergo a [4+2] cycloaddition with ester enolates or ketenimine anions to produce diver...

Synthesis and structure-activity relationships of 2-alkylidenethiazolidine-4,5-diones as antibiotic agents.

Bioorg. Med. Chem. 13(14) , 4402-7, (2005)

2-Alkylidenethiazolidine-4,5-diones were prepared by novel one-pot cyclizations of arylacetonitriles with isothiocyanates and ethyl 2-chloro-2-oxoacetate. The products show antibiotic activity against...