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Butantrone

Names

[ CAS No. ]:
75464-11-8

[ Name ]:
Butantrone

[Synonym ]:
10-butyryl-1,8-dihydroxy-9-anthron
Butantrona [Spanish]
Butantronum [Latin]
Dithranol,10-butyryl
1,8-dihydroxy-10-(1'-oxobutyl)-9(10H)-anthracenone
9(10H)-ANTHRACENONE,1,8-DIHYDROXY-10-(1-OXOBUTYL)
Butantrona
1,8-dihydroxy-10-butyrylanthrone
10-Butyryl dithranol
10-butyryl-1,8-dihydroxy-9(10H)-anthracenone
Butantrone

Chemical & Physical Properties

[ Density]:
1.324g/cm3

[ Boiling Point ]:
490.1ºC at 760 mmHg

[ Molecular Formula ]:
C18H16O4

[ Molecular Weight ]:
296.31700

[ Flash Point ]:
264.3ºC

[ Exact Mass ]:
296.10500

[ PSA ]:
74.60000

[ LogP ]:
3.14330

[ Index of Refraction ]:
1.641

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CB1500000
CHEMICAL NAME :
9(10H)-Anthracenone, 1,8-dihydroxy-10-(1-oxobutyl)-
CAS REGISTRY NUMBER :
75464-11-8
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C18-H16-O4
MOLECULAR WEIGHT :
296.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1579 mg/kg
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from small intestine Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
139 mg/kg
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from small intestine Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ug/plate
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 59,180,1986

Synthetic Route

Precursor & DownStream


Related Compounds