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Dimethylphosphorodithioate

Names

[ CAS No. ]:
756-80-9

[ Name ]:
Dimethylphosphorodithioate

[Synonym ]:
O,O-dimethyl phosphorodithioic acid
dithiophosphorus acid O,O-dimethyl ester
Dimethylphosphorodithioate
EINECS 212-053-9
O,O-Dimethyl phosphorodithioate
Dimethyl phosphodithionate
dithiophosphoric acid-O.O-dimethyl ester
O,O-Dimethyldithiophosphate
O,O-dimethyldithiophosphoric acid
Dimethyldithiophosphoric acid
O,O-Dimethyl hydrogen dithiophosphate
Phosphorodithioic acid,O,O-dimethyl ester

Chemical & Physical Properties

[ Density]:
1.29

[ Boiling Point ]:
65ºC

[ Molecular Formula ]:
C2H7O2PS2

[ Molecular Weight ]:
158.18000

[ Flash Point ]:
71.2ºC

[ Exact Mass ]:
157.96300

[ PSA ]:
99.16000

[ LogP ]:
2.08410

[ Index of Refraction ]:
1.535

[ Storage condition ]:
-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TE0525000
CHEMICAL NAME :
Phosphorodithioic acid, O,O-dimethyl ester
CAS REGISTRY NUMBER :
756-80-9
BEILSTEIN REFERENCE NO. :
0635993
LAST UPDATED :
199710
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C2-H7-O2-P-S2
MOLECULAR WEIGHT :
158.18
WISWESSER LINE NOTATION :
SHPS&O1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1175,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1175,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1175,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1550 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 28,599,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
68500 ug/kg
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases
REFERENCE :
AITDAQ Archiwum Immunologii i Terapii Doswiadczalnej. (Warsaw, Poland) V.1-9, 1953-61. For publisher information, see AITEAT. Volume(issue)/page/year: 6,333,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
1400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 39(4),86,1974 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
DOSE :
161 mg/m3/6H
SEX/DURATION :
male 11 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
REFERENCE :
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0385-0547

Synthetic Route

Precursor & DownStream


Related Compounds