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Benzo[a]heptalen-9(5H)-one,6,7-dihydro-1,2,3-trimethoxy-7-(methylamino)-10-(methylthio)-, (7S)-

Names

[ CAS No. ]:
76129-11-8

[ Name ]:
Benzo[a]heptalen-9(5H)-one,6,7-dihydro-1,2,3-trimethoxy-7-(methylamino)-10-(methylthio)-, (7S)-

[Synonym ]:
(S)-1,2,3-Trimethoxy-7-methylamino-10-methylmercapto-6,7-dihydro-5H-benzo[a]heptalen-9-on
(S)-1,2,3-trimethoxy-7-methylamino-10-methylsulfanyl-6,7-dihydro-5H-benzo[a]heptalen-9-one
thiodemecolcine

Chemical & Physical Properties

[ Density]:
1.23g/cm3

[ Boiling Point ]:
631.2ºC at 760 mmHg

[ Molecular Formula ]:
C21H25NO4S

[ Molecular Weight ]:
387.49300

[ Flash Point ]:
335.5ºC

[ Exact Mass ]:
387.15000

[ PSA ]:
82.09000

[ LogP ]:
4.05910

[ Index of Refraction ]:
1.607

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DF9485250
CHEMICAL NAME :
Benzo(a)heptalen-9(5H)-one, 6,7-dihydro-7-(methylamino)-10-(methylthio)-1,2,3-tri methoxy-, (S)-
CAS REGISTRY NUMBER :
76129-11-8
BEILSTEIN REFERENCE NO. :
3170982
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H25-N-O4-S
MOLECULAR WEIGHT :
387.53

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 28,1204,1985

Synthetic Route

Precursor & DownStream


Related Compounds