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Benzamide, 4-nitro-N-(5,6,7,9-tetrahydro-1,2,3, 10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-

Names

[ CAS No. ]:
76129-13-0

[ Name ]:
Benzamide, 4-nitro-N-(5,6,7,9-tetrahydro-1,2,3, 10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-

Chemical & Physical Properties

[ Molecular Formula ]:
C27H26N2O8

[ Molecular Weight ]:
506.50400

[ Exact Mass ]:
506.16900

[ PSA ]:
128.91000

[ LogP ]:
4.98780

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GH0820000
CHEMICAL NAME :
Colchicine, N-deacetyl-N-(p-nitrobenzoyl)-
CAS REGISTRY NUMBER :
76129-13-0
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C27-H26-N2-O8
MOLECULAR WEIGHT :
506.55
WISWESSER LINE NOTATION :
L B677 MV&T&J CO1 DO1 EO1 JMVR DNW& NO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
19 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,636,1981

Synthetic Route

Precursor & DownStream


Related Compounds