2-(N-(1-(5-Chloro-2-methoxybenzyl)-4-piperidyl)methylamino)pyrimidine dihydrochloride
Names
[ CAS No. ]:
76167-81-2
[ Name ]:
2-(N-(1-(5-Chloro-2-methoxybenzyl)-4-piperidyl)methylamino)pyrimidine dihydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
474.6ºC at 760 mmHg
[ Molecular Formula ]:
C18H25Cl3N4O
[ Molecular Weight ]:
419.77600
[ Flash Point ]:
240.8ºC
[ Exact Mass ]:
418.10900
[ PSA ]:
41.49000
[ LogP ]:
4.78130
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UV8113000
- CHEMICAL NAME :
- Pyrimidine, 2-(N-(1-(5-chloro-2-methoxybenzyl)-4-piperidyl)methyl amino)-, dihydrochloride
- CAS REGISTRY NUMBER :
- 76167-81-2
- LAST UPDATED :
- 199112
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C18-H23-Cl-N4-O.2Cl-H
- MOLECULAR WEIGHT :
- 419.82
- WISWESSER LINE NOTATION :
- T6N CNJ BN1&- DT6NTJ A1R CG FO1 &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >300 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Vascular - relaxation (isolated tissues)
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 35,951,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >100 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Vascular - relaxation (isolated tissues)
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 35,951,1980