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Bis(2-(N-methyl-N-(1-benzyl-4-piperidyl))amino-5-pyrimidyl)methane

Names

[ CAS No. ]:
76167-83-4

[ Name ]:
Bis(2-(N-methyl-N-(1-benzyl-4-piperidyl))amino-5-pyrimidyl)methane

Chemical & Physical Properties

[ Density]:
1.198g/cm3

[ Boiling Point ]:
724.6ºC at 760 mmHg

[ Molecular Formula ]:
C35H44N8

[ Molecular Weight ]:
576.77700

[ Flash Point ]:
392ºC

[ Exact Mass ]:
576.36900

[ PSA ]:
64.52000

[ LogP ]:
4.93480

[ Index of Refraction ]:
1.646

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV9332000
CHEMICAL NAME :
Pyrimidine, 5,5'-methylenebis(2-(N-(1-benzyl-4-piperidyl)methylam ino)-
CAS REGISTRY NUMBER :
76167-83-4
LAST UPDATED :
199112
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C35-H44-N8
MOLECULAR WEIGHT :
576.87
WISWESSER LINE NOTATION :
T6N CNJ BN1&- DT6NTJ A1R&& E1- ET6N CNJ BN1&- DT6NTJ A1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>300 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - changes in motor activity (specific assay) Vascular - relaxation (isolated tissues)
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 35,951,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>100 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - changes in motor activity (specific assay) Vascular - relaxation (isolated tissues)
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 35,951,1980

Related Compounds