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9AzNue5Ac

Names

[ CAS No. ]:
76487-51-9

[ Name ]:
9AzNue5Ac

[Synonym ]:
D-glycero-D-galacto-2-Nonulopyranosonic acid, 5-(acetylamino)-9-azido-3,5,9-trideoxy-
(6R)-5-Acetamido-6-[(1R,2R)-3-azido-1,2-dihydroxypropyl]-3,5-dideoxy-L-threo-hex-2-ulopyranosonic acid

Biological Activity

[Description]:

9AzNue5Ac, 9-azido-9-deoxy-N-acetylneuraminic acid, is a click chemistry reagent and a Neu5Ac analogue with the substitution of 9-hydroxyl group with an azide. 9AzNue5Ac could be metabolized and incorporated into sialoglycans in living cells and mice. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

[References]

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.  

Chemical & Physical Properties

[ Molecular Formula ]:
C11H18N4O8

[ Molecular Weight ]:
334.283

[ Exact Mass ]:
334.112457

[ LogP ]:
-1.86

Related Compounds