3β-Acetoxy-hop-22(29)-ene

Names

[ CAS No. ]:
76582-61-1

[ Name ]:
3β-Acetoxy-hop-22(29)-ene

Biological Activity

[Description]:

3β-Acetoxy-hop-22(29)-ene (compound 1) is a potent anti-inflammatory agent. 3β-Acetoxy-hop-22(29)-ene shows high inhibitory activity of yeast α-glucosidase, with an IC50 of 5.74 μM. 3β-Acetoxy-hop-22(29)-ene inhibits MPO (myeloperoxidase) activity in a dose-dependent manner in mouse ear edema model induced by 12-O-tetradecanoylphorbol acetate (TPA), with an IC50 of 0.23 μmol/ear[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[Target]

IC50: 0.23 μmol/ear (MPO), 5.74 ± 0.49 μM (yeast α-glucosidase)[1]


[References]

[1]. López-Huerta FA, et al. Hopane-type triterpenes from Cnidoscolus spinosus and their bioactivities. Bioorg Chem. 2020 Jul;100:103919.

Chemical & Physical Properties

[ Molecular Formula ]:
C32H52O2

[ Molecular Weight ]:
468.75

Related Compounds