4-Nitrophenyl chloroformate

Names

[ Name ]:
4-Nitrophenyl chloroformate

[Synonym ]:
Nitrophenyl chloroforMate
4-Nitrophenyl Chlorooate
4-nitrophenoxycarbonyl chloride
Carbonochloridic acid, 4-nitrophenyl ester
P-NITROPHENYL CHLOROCARBONATE
4-Nitrophenyl chloroformate
p-nitrophenyloxycarbonyl chloride
chloroformic acid 4-nitrophenyl ester
chlorocarbonic acid p-nitrophenyl ester
4-Nitrophenylchlorocarbonat
4-NITROPHENYL CHLOROCARBONATE
PNPCF
4-Nitrophenylchloroformate
Formic acid, chloro-, p-nitrophenyl ester
PARA-NITROPHENYL CHLOROFORMATE
EINECS 231-706-9
4-Nitrophenyl carbonochloridate
MFCD00007321
p-Nitrophenol chloroformate
P-NITROPHENYL CHLOROFORMATE

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
283.6±13.0 °C at 760 mmHg

[ Melting Point ]:
77-79 °C(lit.)

[ Molecular Formula ]:
C₇H₄ClNO₄

[ Molecular Weight ]:
201.564

[ Flash Point ]:
125.3±19.8 °C

[ Exact Mass ]:
200.982880

[ PSA ]:
72.12000

[ LogP ]:
2.84

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.577

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Incompatible with strong bases, acids. Combustible.

[ Water Solubility ]:
decomposes

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R23/24/25;R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S38-S28A-S36-S16

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
29159020

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles

In vivo performance and biocompatibility of a subcutaneous implant for real-time glucose-responsive insulin delivery.

Diabetes Technol. Ther. 17(4) , 255-67, (2015)

An implantable, glucose-responsive insulin delivery microdevice was reported previously by our group, providing rapid insulin release in response to hyperglycemic events and efficacy in vivo over a 1-...

Cysteine-Functionalized Nanostructured Lipid Carriers for Oral Delivery of Docetaxel: A Permeability and Pharmacokinetic Study.

Mol. Pharm. 12 , 2384-95, (2015)

Here we report the development and evaluation of cysteine-modified nanostructured lipid carriers (NLCs) for oral delivery of docetaxel (DTX). The NLCs ensure high encapsulation efficiency of docetaxel...

Microstructured dextran hydrogels for burst-free sustained release of PEGylated protein drugs.

Biomaterials 63 , 146-57, (2015)

Hydrogels have gained significant attention as ideal delivery vehicles for protein drugs. However, the use of hydrogels for protein delivery has been restricted because their porous structures inevita...