Koshland's Reagent 1

Names

[ CAS No. ]:
772-33-8

[ Name ]:
Koshland's Reagent 1

[Synonym ]:
o-Cresol, α-bromo-4-nitro-
Phenol, 2- (bromomethyl)-4-nitro-
Phenol, 2-(bromomethyl)-4-nitro-
α-Bromo-4-nitro-o-cresol
EINECS 212-248-9
MFCD00007340
2-Hydroxy-5-nitrobenzyl Bromide
2-(Bromomethyl)-4-nitrophenol
a-Bromo-4-nitro-o-cresol
Koshland's Reagent 1

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
383.0±32.0 °C at 760 mmHg

[ Melting Point ]:
144-149 °C(lit.)

[ Molecular Formula ]:
C₇H₆BrNO₃

[ Molecular Weight ]:
232.031

[ Flash Point ]:
185.5±25.1 °C

[ Exact Mass ]:
230.953094

[ PSA ]:
66.05000

[ LogP ]:
2.27

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.654

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2908999090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2908999090

[ Summary ]:
2908999090 halogenated, sulphonated, nitrated or nitrosated derivatives of phenols or phenol-alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Effect of protein-modifying reagents on ecto-apyrase from rat brain.

Int. J. Biochem. Cell Biol. 32(1) , 105-13, (2000)

We have tested several chemical modifiers to investigate which amino acid residues, present in the primary structure of the ecto-apyrase, could be involved in catalysis. Synaptosomes from cerebral cor...

Role of tyrosine and tryptophan in chemically modified serum albumin on its tissue distribution.

Biol. Pharm. Bull. 29(9) , 1926-30, (2006)

To investigate the effect of functional groups in bovine serum albumin (BSA) on its tissue distribution characteristics, tyrosine (Tyr) or tryptophan (Trp) residues of BSA were chemically modified by ...

Chemical modification of amino acid residues in glycerinated Vorticella stalk and Ca(2+)-induced contractility.

Cell Motil. Cytoskeleton 36(4) , 305-12, (1997)

The glycerinated stalk of the peritrich ciliate Vorticella, was treated with various reagents to chemically modify the amino acid residues. The influences of these modifcations on spasmoneme contracti...