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dihydromevinolin

Names

[ CAS No. ]:
77517-29-4

[ Name ]:
dihydromevinolin

Chemical & Physical Properties

[ Density]:
1.1g/cm3

[ Boiling Point ]:
534.8ºC at 760 mmHg

[ Molecular Formula ]:
C24H38O5

[ Molecular Weight ]:
406.55600

[ Flash Point ]:
174.5ºC

[ Exact Mass ]:
406.27200

[ PSA ]:
72.83000

[ LogP ]:
4.27540

[ Index of Refraction ]:
1.52

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Articles

Total synthesis and biological evaluation of structural analogues of compactin and dihydromevinolin.

J. Med. Chem. 30(10) , 1858-73, (1987)

The full experimental details for the total synthesis of (+)-compactin and 19 structural analogues are reported. We have evaluated three classes of analogues as inhibitors of 3-hydroxy-3-methylglutary...

Dihydromevinolin, a potent hypocholesterolemic metabolite produced by Aspergillus terreus.

J. Antibiot. 34(5) , 507-12, (1981)

A new, potent hypocholesterolemic agent is produced by cultures of Aspergillus terreus. The isolation of the compound and its characterization as 4a,5-dihydromevinolin containing a trans-fused octahyd...


More Articles


Related Compounds