dihydromevinolin
Names
[ CAS No. ]:
77517-29-4
[ Name ]:
dihydromevinolin
Chemical & Physical Properties
[ Density]:
1.1g/cm3
[ Boiling Point ]:
534.8ºC at 760 mmHg
[ Molecular Formula ]:
C24H38O5
[ Molecular Weight ]:
406.55600
[ Flash Point ]:
174.5ºC
[ Exact Mass ]:
406.27200
[ PSA ]:
72.83000
[ LogP ]:
4.27540
[ Index of Refraction ]:
1.52
Safety Information
[ RIDADR ]:
NONH for all modes of transport
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Med. Chem. 30(10) , 1858-73, (1987)
The full experimental details for the total synthesis of (+)-compactin and 19 structural analogues are reported. We have evaluated three classes of analogues as inhibitors of 3-hydroxy-3-methylglutary...
Dihydromevinolin, a potent hypocholesterolemic metabolite produced by Aspergillus terreus.J. Antibiot. 34(5) , 507-12, (1981)
A new, potent hypocholesterolemic agent is produced by cultures of Aspergillus terreus. The isolation of the compound and its characterization as 4a,5-dihydromevinolin containing a trans-fused octahyd...