AUDA-BE
Names
[ CAS No. ]:
776300-37-9
[ Name ]:
AUDA-BE
Biological Activity
[Description]:
The prodrug of AUDA, a potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 50 nM and 100 nM for mouse sEH and human sEH, respectively; prevents LPS-induced mortality and preserved systolic blood pressure, reduces NO production in mice.
[References]
References 1. Morisseau C, et al. Biochem Pharmacol. 2002 May 1;63(9):1599-608. 2. Schmelzer KR, et al. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9772-7. 3. Motoki A, et al. Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H2128-34. View Related Products by Target Other Targets
Chemical & Physical Properties
[ Molecular Formula ]:
C27H48N2O3
[ Molecular Weight ]:
448.692