Cyclopent[i]azacyclononadecine-7,17(8H,19H)-dione,9,10,13,14,15,16,20,20a-octahydro-15,18-dihydroxy-19-methoxy-2-methyl-9-phenyl-,(1Z,3E,5E,9S,11E,15S,19S,20aR)-
Names
[ CAS No. ]:
77642-19-4
[ Name ]:
Cyclopent[i]azacyclononadecine-7,17(8H,19H)-dione,9,10,13,14,15,16,20,20a-octahydro-15,18-dihydroxy-19-methoxy-2-methyl-9-phenyl-,(1Z,3E,5E,9S,11E,15S,19S,20aR)-
[Synonym ]:
Antibiotic KG-2245
KG-2245
KM-4927
Antibiotic KM-4927
stubomycin
Chemical & Physical Properties
[ Molecular Formula ]:
C29H35NO5
[ Molecular Weight ]:
477.59200
[ Exact Mass ]:
477.25200
[ PSA ]:
95.86000
[ LogP ]:
5.13860
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GY5946700
- CHEMICAL NAME :
- Cyclopent(i)azacyclononadecine-7,17(8H,19H)-dione, 9,10,13,14,15,16,20,20a-octahydro- 15,18-dihydroxy-19-methoxy-2-methyl-9-phenyl-
- CAS REGISTRY NUMBER :
- 77642-19-4
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C29-H35-N-O5
- MOLECULAR WEIGHT :
- 477.65
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Human HeLa cell
- DOSE/DURATION :
- 2500 ug/L
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 34,259,1981