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HOOCCH2O-PEG4-CH2COOH

Names

[ CAS No. ]:
77855-75-5

[ Name ]:
HOOCCH2O-PEG4-CH2COOH

[Synonym ]:
3,6,9,12,15-pentaoxaheptadecane-1,17-dioic acid
3,6,9,12,15-Pentaoxaheptadecanedioic acid

Biological Activity

[Description]:

HOOCCH2O-PEG4-CH2COOH, compound 5, is a symmetric PEG linker, used for the synthesis of the first class of Homo-PROTAC[1].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830.

Chemical & Physical Properties

[ Molecular Formula ]:
C12H22O9

[ Molecular Weight ]:
310.29800

[ Exact Mass ]:
310.12600

[ PSA ]:
120.75000

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds