Gilvocarcin V
Names
[ CAS No. ]:
77879-90-4
[ Name ]:
Gilvocarcin V
[Synonym ]:
Gilvocacin V
1,4-Anhydro-6-deoxy-1-(1-hydroxy-10,12-dimethoxy-6-oxo-8-vinyl-6H-dibenzo[c,h]chromen-4-yl)hexitol
Hexitol, 1,4-anhydro-6-deoxy-1-C-(8-ethenyl-1-hydroxy-10,12-dimethoxy-6-oxo-6H-benzo[d]naphtho[1,2-b]pyran-4-yl)-
gilvocarcin V
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
821.6±65.0 °C at 760 mmHg
[ Molecular Formula ]:
C27H26O9
[ Molecular Weight ]:
494.490
[ Flash Point ]:
280.1±27.8 °C
[ Exact Mass ]:
494.157684
[ PSA ]:
138.82000
[ LogP ]:
4.00
[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C
[ Index of Refraction ]:
1.698
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DI2240000
- CHEMICAL NAME :
- 6H-Benzo(d)naphtho(1,2-b)pyran-6-one, 4-(6-deoxy-alpha-galactofuranosyl)-8-ethenyl- 1-hydroxy-10,12-dimethoxy-
- CAS REGISTRY NUMBER :
- 77879-90-4
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C27-H26-O9
- MOLECULAR WEIGHT :
- 494.53
- WISWESSER LINE NOTATION :
- T E6 B666 COVJ G1U1 IO1 MO1 OQ R- BT5OTJ CQ DQ EYQ1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Bacteria - Bacillus subtilis
- DOSE/DURATION :
- 500 ug/L
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 35,545,1982