UNII:FGB8O5N903
Names
[ CAS No. ]:
78-75-1
[ Name ]:
UNII:FGB8O5N903
[Synonym ]:
1,2-dibromo-propan
1,2-dibromoprpane
Propane, 1,2-dibromo-
1,2-Dobromopropane
Propylene dibromide
2-Bromopropionyl bromide
1,2-Dibrompropan
1,2-Dibromopropane
CH2BrCHBrCH3
2,3-dibromopropane
UNII:FGB8O5N903
EINECS 201-139-1
11,2-DIBROMOPROPANE
MFCD00000148
PROPYLENE BROMIDE
Chemical & Physical Properties
[ Density]:
1.9±0.1 g/cm3
[ Boiling Point ]:
140.4±8.0 °C at 760 mmHg
[ Melting Point ]:
-55 °C
[ Molecular Formula ]:
C3H6Br2
[ Molecular Weight ]:
201.888
[ Flash Point ]:
21.9±17.7 °C
[ Exact Mass ]:
199.883606
[ LogP ]:
2.43
[ Vapour Pressure ]:
7.7±0.2 mmHg at 25°C
[ Index of Refraction ]:
1.511
[ Stability ]:
Stable. Flammable. Incompatible with strong oxidizing agents, strong bases, magnesium.
[ Water Solubility ]:
slightly soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX8574000
- CHEMICAL NAME :
- Propane, 1,2-dibromo-
- CAS REGISTRY NUMBER :
- 78-75-1
- BEILSTEIN REFERENCE NO. :
- 1718884
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C3-H6-Br2
- MOLECULAR WEIGHT :
- 201.91
- WISWESSER LINE NOTATION :
- EY1&1E
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 741 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12 gm/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 676 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
MUTATION DATA
- TEST SYSTEM :
- Rodent - rat
- DOSE/DURATION :
- 75716 ug/kg
- REFERENCE :
- CRTOEC Chemical Research in Toxicology. (American Chemical Soc., Distribution Office Dept. 223, POB 57/36, West End Station, Washington, DC 20037) V.1- 1988- Volume(issue)/page/year: 4,528,1991 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6607 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H226-H302 + H332
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R10;R20/21/22;R36/37/38
[ Safety Phrases ]:
S23-S24/25-S36/37/39-S26-S16
[ RIDADR ]:
UN 1993 3/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
TX8574000
[ Packaging Group ]:
III
[ Hazard Class ]:
3
[ HS Code ]:
29033036
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Preparation
Customs
[ HS Code ]: 29033036
Articles
J. Chromatogr. A. 1407 , 208-15, (2015)
Haloketones (HKs) are unregulated volatile disinfection by-products that show some potential risk even at low concentrations. While EPA Method 551.1 involves conventional liquid-liquid extraction and ...
Simultaneous quantification of trihalomethanes and haloacetic acids in cheese by on-line static headspace gas chromatography-mass spectrometry.J. Chromatogr. A. 1408 , 22-9, (2015)
Trihalomethanes (THMs) and haloacetic acids (HAAs) are the two most prevalent classes of disinfection by-products (DBPs) that are present in treated water. Four THMs and six HAAs are regulated by seve...
[Research concerning rutin semisynthetic derivatives. Synthesis, physico-chemical and microbiological characterisation of some new rutin-isoniazid derivatives].Rev. Med. Chir. Soc. Med. Nat. Iasi. 112(1) , 249-52, (2008)
Isoniazid is one of the most used antituberculosis drugs, but its toxicity is high. In this study, four derivatives of rutin and isoniazid were prepared and their antibacterial and antimycotic activit...