Propionamide
Names
[ CAS No. ]:
79-05-0
[ Name ]:
Propionamide
[Synonym ]:
Propionimidic acid
Carbylamine, ethyl-
Propanimidic acid (VAN)
Ethylcarbylamine
n-propylamide
MONOMETHYLACETAMIDE
Propionamide
Propylamide
Propionimidic acid (VAN)
Propanimidic acid
carboxylic acid methyl amide
MFCD00008039
methylacetamide
Ethylformamide
Methyl acetamide
Propionic acid amide
propionylamine
EINECS 201-172-1
Propanamide
Acetamide, methyl-
propionic amide
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
103.0±23.0 °C at 760 mmHg
[ Melting Point ]:
79 °C
[ Molecular Formula ]:
C3H7NO
[ Molecular Weight ]:
73.094
[ Flash Point ]:
16.1±22.6 °C
[ Exact Mass ]:
73.052765
[ PSA ]:
43.09000
[ LogP ]:
-0.38
[ Vapour Pressure ]:
18.3±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.431
[ Water Solubility ]:
SOLUBLE
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UE2975000
- CHEMICAL NAME :
- Propionamide
- CAS REGISTRY NUMBER :
- 79-05-0
- BEILSTEIN REFERENCE NO. :
- 0969258
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C3-H7-N-O
- MOLECULAR WEIGHT :
- 73.11
- WISWESSER LINE NOTATION :
- ZV2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8000 ppm
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,1243,1989
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 230 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV. Volume(issue)/page/year: 153,895,1911
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UE2975000
[ HS Code ]:
29241900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299036
[ Summary ]:
HS:2924299036 propionamide VAT:17.0% Tax rebate rate:9.0% Supervision conditions:S MFN tariff:6.5% General tariff:30.0%
Articles
Pharm. Biol. 53(4) , 540-7, (2015)
Glycosmis parva Craib (Rutaceae) is reported to have cytotoxic and anti-inflammatory activities by decreasing COX-2 expression.To investigate the effect of G. parva on human colorectal cancer cells ex...
Gamma secretase inhibitors enhance vincristine-induced apoptosis in T-ALL in a NOTCH-independent manner.Apoptosis 19(11) , 1616-26, (2014)
Activating mutations in the NOTCH1 gene are found in over 50 % of T-ALL cases. Since Notch signaling contributes to the leukemia cell survival and growth, targeting Notch signaling using γ-secretase i...
Mass spectrometric characterization of glucuronides formed by a new concept, combining Cunninghamella elegans with TEMPO.J. Pharm. Biomed. Anal. 84 , 278-84, (2013)
A new concept for the production of drug glucuronides is presented and the products formed were characterized using ultra high performance liquid chromatography-high resolution mass spectrometry (UPLC...