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Phenol,4,4'-(1-methylethylidene)bis[2,6-dichloro-

Names

[ CAS No. ]:
79-95-8

[ Name ]:
Phenol,4,4'-(1-methylethylidene)bis[2,6-dichloro-

[Synonym ]:
2,6-dichloro-4-[2-(3,5-dichloro-4-hydroxyphenyl)propan-2-yl]phenol
EINECS 201-237-4
MFCD00002178

Chemical & Physical Properties

[ Density]:
1.479 g/cm3

[ Boiling Point ]:
401.9ºC at 760 mmHg

[ Melting Point ]:
134ºC

[ Molecular Formula ]:
C15H12Cl4O2

[ Molecular Weight ]:
366.06700

[ Flash Point ]:
196.8ºC

[ Exact Mass ]:
363.95900

[ PSA ]:
40.46000

[ LogP ]:
6.03730

[ Index of Refraction ]:
1.627

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SL6250000
CHEMICAL NAME :
Phenol, 4,4'-isopropylidenebis(2,6-dichloro-
CAS REGISTRY NUMBER :
79-95-8
BEILSTEIN REFERENCE NO. :
2059573
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C15-H12-Cl4-O2
MOLECULAR WEIGHT :
366.07
WISWESSER LINE NOTATION :
QR BG FG DX1&1&R DQ BG FG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,536,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7432 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(2),64,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5050 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(2),64,1984 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
67500 mg/kg/45D-I
TOXIC EFFECTS :
Blood - microcytosis with or without anemia Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(2),64,1984
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
9750 mg/kg/26W-I
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells Blood - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(2),64,1984

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-37/39

Synthetic Route

Precursor & DownStream

Precursor

DownStream


Related Compounds