LTB4_20-hydroxy

Names

[ Name ]:
LTB4_20-hydroxy

[Synonym ]:
20-hydroxy-leukotriene B4
20-Hydroxy-LTB4
20-hydroxyleukotriene
hydroxyleukotriene B4
(5S,6Z,8E,10E,12R,14Z)-5,12,20-Trihydroxy-6,8,10,14-icosatetraenoic acid
LTB4_20-hydroxy
20-OH-LTB4
5S,12R,20-TRIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENOIC ACID
6,8,10,14-Eicosatetraenoic acid, 5,12,20-trihydroxy-, (5S,6Z,8E,10E,12R,14Z)-
MFCD00065858

Biological Activity

[Description]:

20-Hydroxy-leukotriene B4 is an endogenous metabolite present in Urine that can be used for the research of Sjogren Larsson Syndrome[1][2].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[Target]

Human Endogenous Metabolite

[In Vitro]

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].

[References]

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.

[2]. Willemsen MA, et al. Defective metabolism of leukotriene B4 in the Sjögren-Larsson syndrome. J Neurol Sci. 2001 Jan 15;183(1):61-7.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
581.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₃₂O₅

[ Molecular Weight ]:
352.465

[ Flash Point ]:
319.7±26.6 °C

[ Exact Mass ]:
352.224976

[ PSA ]:
97.99000

[ LogP ]:
2.05

[ Vapour Pressure ]:
0.0±3.7 mmHg at 25°C

[ Index of Refraction ]:
1.542

Safety Information

[ Hazard Codes ]:
F: Flammable;Xi: Irritant;

[ Risk Phrases ]:
11-36/37/38

[ Safety Phrases ]:
16-26-36

[ RIDADR ]:
UN 1170 3/PG 2

LTB4_20-hydroxy

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds