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Azido-PEG1-CH2CO2H

Names

[ CAS No. ]:
79598-48-4

[ Name ]:
Azido-PEG1-CH2CO2H

[Synonym ]:
(2-Azidoethoxy)acetic acid
MFCD24452584
Acetic acid, 2-(2-azidoethoxy)-

Biological Activity

[Description]:

Azido-PEG1-CH2CO2H is a PROTAC linker, which refers to the alkyl/ether composition. Azido-PEG1-CH2CO2H can be used in the synthesis of PROTAC BRD4 Degrader-1[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

Alkyl/ether


[References]

[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide.Bioorg Med Chem. 2020 Jan 1;28(1):115228.

Chemical & Physical Properties

[ Molecular Formula ]:
C4H7N3O3

[ Molecular Weight ]:
145.117

[ Exact Mass ]:
145.048737

[ LogP ]:
-0.38

[ Storage condition ]:
-20°C

Related Compounds