Casuarictin

Names

[ Name ]:
Casuarictin

[Synonym ]:
Sanguiin H 11

Biological Activity

[Description]:

Casuarictin is a potent and competitive α-glucosidase inhibitor with an IC50 of 0.21 μg/mL. Casuarictin is a presenilin stabilization factor like protein (PSFL) protein inhibitor. Casuarictin can be used for Alzheimer's disease research[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. Yang Xu, et al. Identification of a novel α-glucosidase inhibitor from Melastoma dodecandrum Lour. fruits and its effect on regulating postprandial blood glucose. Food Chem. 2023 Jan 15:399:133999.

[2]. Rupali Kumari, et al. Casuarictin: A new herbal drug molecule for Alzheimer's disease as inhibitor of presenilin stabilization factor like protein. Heliyon. 2020 Nov 21;6(11):e05546.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₁H₂₈O₂₆

[ Molecular Weight ]:
936.64500

[ Exact Mass ]:
936.08700

[ PSA ]:
444.18000

[ LogP ]:
1.64690

Casuarictin

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream