3-T-BUTYL-5-METHOXY-1,2-BENZENEDIOL

Names

[ Name ]:
3-T-BUTYL-5-METHOXY-1,2-BENZENEDIOL

[Synonym ]:
5-methoxy-3-(2-methyl-2-propanyl)-1,2-benzenediol
5-Methoxy-3-t-butylcatechol
1,2-Benzenediol,3-(1,1-dimethylethyl)-5-methoxy
3-(1,1-Dimethylethyl)-5-methoxy-1,2-benzenediol
3-tert-Butyl-5-methoxy-brenzcatechin
3-tert-Butyl-4,5-dihydroxyanisole
3-tert-BUTYL-5-METHOXYCATECHOL
3-tert-butyl-5-methoxy-pyrocatechol
3-t-Butyl-5-methoxy-1,2-benzenediol

Chemical & Physical Properties

[ Density]:
1.108g/cm3

[ Boiling Point ]:
327.5ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₆O₃

[ Molecular Weight ]:
196.24300

[ Flash Point ]:
151.9ºC

[ Exact Mass ]:
196.11000

[ PSA ]:
49.69000

[ LogP ]:
2.40390

[ Index of Refraction ]:
1.534

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CZ8946000

CHEMICAL NAME :: 1,2-Benzenediol, 3-(1,1-dimethylethyl)-5-methoxy-

CAS REGISTRY NUMBER :: 80284-15-7

BEILSTEIN REFERENCE NO. :: 2366161

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C11-H16-O3

MOLECULAR WEIGHT :: 196.27

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 15 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 241,125,1990

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
CZ8946000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

On the mechanisms of 3-tert-butyl-4-hydroxyanisole- and its metabolites-induced cytotoxicities in isolated rat hepatocytes.

Eur. J. Pharmacol. 270(4) , 341-8, (1994)

The cytotoxic effects of 3-tert-butyl-4-hydroxyanisole (BHA) and its metabolites, 3-tert-butylhydroquinone (tBHQ) and 3-tert-butyl-4,5-dihydroxyanisole (BHA-OH), were investigated in freshly isolated ...

Metabolism of 3-tert-butyl-4-hydroxyanisole to 3-tert-butyl-4,5-dihydroxyanisole by rat liver microsomes.

Cancer Res. 45(4) , 1507-10, (1985)

3-tert-Butylhydroxyanisole (3-BHA) is an antioxidant which can have a modulating effect on chemical carcinogenesis. Information concerning the metabolism of 3-BHA is incomplete. In the present study, ...

Initiating activity of 3-tert-butyl-4-hydroxyanisole (3-BHA) and its metabolites in two-stage transformation of BALB/3T3 cells.

Carcinogenesis 11(11) , 1985-8, (1990)

3-tert-Butyl-4-hydroxyanisole (3-BHA) and its metabolites, tert-butyl-1,4-benzoquinone (BQ) and 3-tert-butyl-5-methoxy-1,2-benzoquinone (BHAoQ), were tested for initiating activity in a two-stage tran...