(E)-7-[2-morpholin-4-yl-3-oxo-5-[(4-phenylphenyl)methoxy]cyclopentyl]hept-4-enoic acid
Names
[ CAS No. ]:
81443-73-4
[ Name ]:
(E)-7-[2-morpholin-4-yl-3-oxo-5-[(4-phenylphenyl)methoxy]cyclopentyl]hept-4-enoic acid
Chemical & Physical Properties
[ Density]:
1.21g/cm3
[ Boiling Point ]:
657.5ºC at 760 mmHg
[ Molecular Formula ]:
C29H35NO5
[ Molecular Weight ]:
477.59200
[ Flash Point ]:
351.4ºC
[ Exact Mass ]:
477.25200
[ PSA ]:
76.07000
[ LogP ]:
4.66770
[ Index of Refraction ]:
1.603
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MJ9651150
- CHEMICAL NAME :
- 4-Heptenoic acid, 7-(5-((1,1'-biphenyl)-4-ylmethoxy)-2-(4-morpholinyl)- 3-oxocyclopentyl)-, (1-alpha(Z),2-beta,5-alpha)-(+-)-
- CAS REGISTRY NUMBER :
- 81443-73-4
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C29-H35-N-O5
- MOLECULAR WEIGHT :
- 477.65
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 750 mg/kg
- SEX/DURATION :
- female 12-16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - body wall
- REFERENCE :
- ParMM# Personal Communication from M.M. Parkinson, Glaxo Group Research Limited, Ware, Hertfordshire, SG12 0DJ, UK, Mar. 24, 1987 Volume(issue)/page/year: 24MAR1987
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1500 mg/kg
- SEX/DURATION :
- female 12-16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 39,537,1989