2-phenyl-1,3,4-oxadiazole
Names
[ CAS No. ]:
825-56-9
[ Name ]:
2-phenyl-1,3,4-oxadiazole
[Synonym ]:
phenyl-[1,3,4]oxadiazole
Phenyl-[1,3,4]oxadiazol
5-phenyl-1,3,4-oxadiazole
1,3,4-OXADIAZOLE,2-PHENYL
2-phenyl-1,3,4-oxadiazole
1,3,4-Oxadiazole, 2-phenyl-
2-Fenil-1,3,4-ossadiazolo [Italian]
2-phenyl-[1,3,4]oxadiazole
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
253.8±23.0 °C at 760 mmHg
[ Molecular Formula ]:
C8H6N2O
[ Molecular Weight ]:
146.146
[ Flash Point ]:
111.0±16.6 °C
[ Exact Mass ]:
146.048019
[ PSA ]:
38.92000
[ LogP ]:
1.31
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.547
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RO0811300
- CHEMICAL NAME :
- 1,3,4-Oxadiazole, 2-phenyl-
- CAS REGISTRY NUMBER :
- 825-56-9
- BEILSTEIN REFERENCE NO. :
- 0118804
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C8-H6-N2-O
- MOLECULAR WEIGHT :
- 146.16
- WISWESSER LINE NOTATION :
- T5NN DOJ CR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 440 mg/kg
- TOXIC EFFECTS :
- Behavioral - anticonvulsant Behavioral - somnolence (general depressed activity)
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 121,443,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 387 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 13,629,1958
Safety Information
[ HS Code ]:
2934999090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%