2-Ethylhexyl trans-4-methoxycinnamate
Names
[ CAS No. ]:
83834-59-7
[ Name ]:
2-Ethylhexyl trans-4-methoxycinnamate
[Synonym ]:
UNII:F547714O0V
2-Propenoic acid, 3-(4-methoxyphenyl)-, 2-ethylhexyl ester, (2Z)-
MFCD00072582
2-Ethylhexyl (2Z)-3-(4-methoxyphenyl)acrylate
4-methoxycinnamic acid 2-ethylhexyl ester
EINECS 226-775-7
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
405.3±20.0 °C at 760 mmHg
[ Molecular Formula ]:
C18H26O3
[ Molecular Weight ]:
290.397
[ Flash Point ]:
171.6±16.4 °C
[ Exact Mass ]:
290.188202
[ PSA ]:
35.53000
[ LogP ]:
5.66
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.515
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
24/25-36-26
[ RIDADR ]:
NONH for all modes of transport
Articles
J. Sci. Ind. Res. 65(10) , 808, (2006)
Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI typ...
Developing structure-activity relationships for the prediction of hepatotoxicity.Chem. Res. Toxicol. 23 , 1215-22, (2010)
Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ...
A predictive ligand-based Bayesian model for human drug-induced liver injury.Drug Metab. Dispos. 38 , 2302-8, (2010)
Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predicti...