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chlorproethazine

Names

[ CAS No. ]:
84-01-5

[ Name ]:
chlorproethazine

[Synonym ]:
EINECS 201-510-8
Chlorproethazinum [INN-Latin]
[3-(2-chloro-phenothiazin-10-yl)-propyl]-diethyl-amine
Chlorproethazine
diethyl-[3-(2-chloro-phenothiazin-10-yl)-propyl]-amine
2-chloro-10-{3-(diethylamino)propyl}phenothiazine
Chlorproethazine [INN]
Clorproetazina [INN-Spanish]
Neuriplege
Chlorproethazin
RP 4909
Diaethyl-[3-(2-chlor-phenothiazin-10-yl)-propyl]-amin

Chemical & Physical Properties

[ Melting Point ]:
153-156ºC

[ Molecular Formula ]:
C19H23ClN2S

[ Molecular Weight ]:
346.91700

[ Exact Mass ]:
346.12700

[ PSA ]:
31.78000

[ LogP ]:
5.73960

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SN7875000
CHEMICAL NAME :
Phenothiazine, 2-chloro-10-(3-(diethylamino)propyl)-
CAS REGISTRY NUMBER :
84-01-5
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C19-H23-Cl-N2-S
MOLECULAR WEIGHT :
346.95
WISWESSER LINE NOTATION :
T C666 BN ISJ B3N2&2 EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
325 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
16 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JJTOEX Japanese Journal of Toxicology. (Yakugyo Jihosha, Hokushin Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo, 101, Japan) V.1- 1988- Volume(issue)/page/year: 4,105,1991

Safety Information

[ HS Code ]:
2934300000

Customs

[ HS Code ]: 2934300000

[ Summary ]:
2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds