Ginger extract

Names

[ Name ]:
Ginger extract

[Synonym ]:
(5S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one
3-Decanone, 1-(4-hydroxy-3-methoxyphenyl)-5-methyl-, compd. with (4E)-1-(4-hydroxy-3-methoxyphenyl)-4-decen-3-one (1:1)
(4E)-1-(4-Hydroxy-3-methoxyphenyl)-4-decen-3-one - 1-(4-hydroxy-3-methoxyphenyl)-5-methyl-3-decanone (1:1)

Biological Activity

[Description]:

Ginger extract exhibits anti-cancer, anti-inflammatory and chemotherapeutic effects in vivo[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

[In Vivo]

Ginger extract (oral gavage; 100 mg/kg; 8 weeks) reduces the incidence of liver neoplasms in rats, it is able to block the elevated expression of NF-κB in liver cancer-induced rats[1]. Animal Model: Male Wistar rat[1] Dosage: 100 mg/kg Administration: Oral gavage; 8 weeks Result: Exhibits anti-cancer effects in the liver cancer-induced group (CDE).

[References]

[1]. Shafina Hanim Mohd Habib, et al. Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats. Clinics (Sao Paulo). 2008 Dec;63(6):807-13.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₃₄O₄

[ Molecular Weight ]:
350.49200

[ Flash Point ]:
76℃

[ Exact Mass ]:
350.24600

[ PSA ]:
66.76000

[ LogP ]:
4.79420

[ Index of Refraction ]:
n20/D1.527

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H304-H315-H319

[ Precautionary Statements ]:
P301 + P310-P305 + P351 + P338-P331

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
36/38-65

[ Safety Phrases ]:
36/37/39-62

Articles

Toxicological effects of pet food ingredients on canine bone marrow-derived mesenchymal stem cells and enterocyte-like cells.

J. Appl. Toxicol. 36 , 189-98, (2016)

We developed an in vitro method to assess pet food ingredients safety. Canine bone marrow-derived mesenchymal stem cells (BMSC) were differentiated into enterocyte-like cells (ELC) to assess toxicity ...