2,6-Dimethyl-3,5-diethoxycarbonyl-4-(o-difluoromethylsulfonylphenyl)-1 ,4-dihydropyridine
Names
[ CAS No. ]:
84761-75-1
[ Name ]:
2,6-Dimethyl-3,5-diethoxycarbonyl-4-(o-difluoromethylsulfonylphenyl)-1 ,4-dihydropyridine
[Synonym ]:
t0501-2663
Chemical & Physical Properties
[ Density]:
1.279g/cm3
[ Boiling Point ]:
554.5ºC at 760 mmHg
[ Molecular Formula ]:
C20H23F2NO6S
[ Molecular Weight ]:
443.46200
[ Flash Point ]:
289.1ºC
[ Exact Mass ]:
443.12100
[ PSA ]:
107.15000
[ LogP ]:
4.45350
[ Index of Refraction ]:
1.516
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US7969700
- CHEMICAL NAME :
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(o-((difluoromethyl)sulfonyl)phenyl)- 2,6-dimethyl-, diethyl ester
- CAS REGISTRY NUMBER :
- 84761-75-1
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C20-H23-F2-N-O6-S
- MOLECULAR WEIGHT :
- 443.50
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 355 mg/kg
- TOXIC EFFECTS :
- Vascular - BP lowering not characterized in autonomic section Vascular - regional or general arteriolar or venous dilation
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 16,817,1982