(S)-Benzyl (1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamate

Names

[ Name ]:
(S)-Benzyl (1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamate

[Synonym ]:
N-Z-L-Trp-Bt
benzyl N-[(1S)-2-(1H-1,2,3-benzotriazol-1-yl)-1-(1H-indol-3-ylmethyl)-2-oxoethyl]carbamate
Z-TRP-BT
Cbz-L-Trp-Bt
Z-L-Trp-Bt
(S)-benzyl [1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-(benzylthio)-1-oxopropan-2-yl]carbamate

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₁N₅O₃

[ Molecular Weight ]:
439.46600

[ Exact Mass ]:
439.16400

[ PSA ]:
101.90000

[ LogP ]:
4.48140

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

DownStream

Articles

Benzotriazole-mediated syntheses of depsipeptides and oligoesters.

J. Org. Chem. 76 , 4884-4893, (2011)

Reactions of O-Pg(α-hydroxyacyl)benzotriazoles with (a) unprotected α-hydroxycarboxylic acids, (b) amino acids, and (c) amines afforded, respectively, chirally pure (a) oligoesters, (b) depsidipeptide...

Efficient preparation of aminoxyacyl amides, aminoxy hybrid peptides, and alpha-aminoxy peptides.

J. Org. Chem. 74th ed.,, 8690-8694, (2009)

N-(Pg-alpha-aminoxy acids) 1a-g are converted to N-(Pg-alpha-aminoxyacyl)benzotriazoles 2a-g, which react under mild conditions with amines, alpha-amino acids/alpha-dipeptides, and alpha-aminoxy acids...

Abdelmajeid, A.; Tala, S. R.; Amine, M. S.; Katritzky, A. R.

Synthesis , 2995-3005, (2011)