N-(4-Methanesulfonyl-2-nitrophenyl)-2H-1, 3-benzodioxol-5-amine

Names

[ Name ]:
N-(4-Methanesulfonyl-2-nitrophenyl)-2H-1, 3-benzodioxol-5-amine

[Synonym ]:
MFCD06679104

Biological Activity

[Description]:

MSNBA is a specific inhibitor of GLUT5 fructose transport in proteoliposomes. MSNBA competitively inhibits GLUT5 fructose uptake with a KI of 3.2±0.4?μM in MCF7 cells[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. George Thompson AM, et al. Discovery of a specific inhibitor of human GLUT5 by virtual screening and in vitro transport evaluation. Sci Rep. 2016 Apr 14;6:24240.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₂N₂O₆S

[ Molecular Weight ]:
336.32

Safety Information

[ Hazard Codes ]:
Xn