1-Chloromethyl naphthalene

Names

[ CAS No. ]:
86-52-2

[ Name ]:
1-Chloromethyl naphthalene

[Synonym ]:
L66J B1G
Naphthalene, α-(chloromethyl)-
1-CHLOROMETHYLNAPHTHYL
Naphthalene, 1-(chloromethyl)-
α-Naphthylmethyl chloride
EINECS 201-678-2
1-chloromethyl-naphthalen
α-(Chloromethyl)naphthalene
1-(Chloromethyl)naphthalene
chloromethylnaphthalene
naphth-1-ylmethyl chloride
1-menaphthylchloride
MFCD04972525
1-Chloromethyl napht
1-(Chlormethyl)naftalen
1-(chloromethyl)-naphthalene
1-Naphtylmethyl chloride
1-CHLORO METHYL NAPHTHALENE

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
291.5±0.0 °C at 760 mmHg

[ Melting Point ]:
32 °C(lit.)

[ Molecular Formula ]:
C₁₁H₉Cl

[ Molecular Weight ]:
176.642

[ Flash Point ]:
129.9±11.4 °C

[ Exact Mass ]:
176.039276

[ LogP ]:
3.72

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.631

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QJ2800000

CHEMICAL NAME :: Naphthalene, 1-chloromethyl-

CAS REGISTRY NUMBER :: 86-52-2

BEILSTEIN REFERENCE NO. :: 0636885

LAST UPDATED :: 199709

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C11-H9-Cl

MOLECULAR WEIGHT :: 176.65

WISWESSER LINE NOTATION :: L66J B1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 890 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IHFCAY Industrial Hygiene Foundation of America, Chemical and Toxicological Series, Bulletin. (Pittsburgh, PA) 1947-69. Volume(issue)/page/year: 6,1,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - body temperature increase

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 24,2583,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IHFCAY Industrial Hygiene Foundation of America, Chemical and Toxicological Series, Bulletin. (Pittsburgh, PA) 1947-69. Volume(issue)/page/year: 6,1,1967 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4412 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 28 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H312-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R21/22;R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S45-S60-S20

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
QJ2800000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
29036990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Nucleophilic dearomatization of chloromethyl naphthalene derivatives via η3-benzylpalladium intermediates: a new strategy for catalytic dearomatization.

Org. Lett. 13(19) , 5402-5, (2011)

Palladium-catalyzed nucleophilic dearomatization of chloromethyl naphthalene derivatives to produce ortho- or para-substituted carbocycles in satisfactory to excellent yields has been developed. The u...

Formation kinetics and spectra of aromatic radicals in solution. Kelley DF, et al.

J. Phys. Chem. 87(11) , 1842-43, (1983)