1-Hydroxyoctadecane-d2

Names

[ CAS No. ]:
86369-69-9

[ Name ]:
1-Hydroxyoctadecane-d2

[Synonym ]:
<1,1-d2>stearyl alcohol
2-Propenoic acid,3-phenyl-,octadecyl ester,(E)
octadecyl 3-phenylacrylate
octadecyl cinnamate
[1,1-2H2]-octadecanol
n-octadecyl trans-cinnamate
1,1-d2-octadecanol
trans-octadecyl-3-phenylpropenoate
1-octadecanol-1,1-d2
1,1-d2-octadecanethiol
trans-Zimtsaeure-octadecylester

Biological Activity

[Description]:

1-Hydroxyoctadecane-d2 is the deuterium labeled 1-Hydroxyoctadecane[1]. 1-Hydroxyoctadecane is an endogenous metabolite.

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Molecular Formula ]:
C18H36D2O

[ Molecular Weight ]:
272.50600

[ Exact Mass ]:
272.30500

[ PSA ]:
20.23000

[ LogP ]:
6.24020

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds